Singulair for Hayfever?
Singulair has become a popular choice for those who would otherwise suffer from asthma most of the time, probably because it is a convenient, once-a-day pill instead of another inhaler. It is also perceived by patients and parents as safer than corticosteroid and bronchodilator asthma inhalers.
During the past couple of years, Singulair has also been marketed for hay fever (allergic rhinitis). However, a study published last month, authored by ENT specialists from Chicago, demonstrated that Singulair, a which costs 3 dollars a day by prescription, was no more effective than sustained-release 240mg Sudafed, an over-the-counter decongestant capsule which costs less than one dollar.
Sudafed was slightly more effective at reducing nasal congestion during the September allergy season in Chicago, and was no more likely to cause side-effects than Singulair.
Homeopathic treatments (equivalent to a placebo) also work rather well for hayfever (allergic rhinitis, sinusitis, and conjunctivitis). A Merck-funded study published in December 2005 [Patel P] showed that 6 weeks of a placebo pill substantially reduced hayfever symptoms in 53% of 1000 adult patients while Singulair did the same for 58% of the other 1000 patients, randomized at 122 medical centers in the United States and Europe. While the difference between 53% and 58% was "statistically significant," the much higher cost of Singulair doesn't seem to me to justify the slightly improved chance of effectiveness. Placebos are also much less likely to cause worrisome dreams than is Singulair.
Patients in the U.S. spend more than 6 billion dollars each year on prescription medicines for hayfever [Yawn, Medscape 2006]. Most of this money is probably spent on non-sedating antihistamines, such as Zyrtec, Clarinex, or Allegra; and for nasal corticosteroid sprays, such as Beconase, Rhinocort, Nasalide, Flonase, Nasonex, or Nasacort. These all cost somebody (patient or insurance) about 75 dollars per month.
However, non-prescription generic Claritin is usually just as effective as the prescription antihistamines and only costs about 3 dollars a month. Rinsing the nose with salt water, such as Sinus Rinse, is even less expensive, often effective at relieving nasal congestion, and has no side-effects. Long-acting nasal decongestant sprays, such as Afrin and generics, can also be used safely for up to ten days, and cost less than 6 dollars for a bottle without a prescription.
In my opinion, people like me with allergic rhinitis should first try the low cost, non-prescription treatments, starting with allergen avoidance, then saline rinses, then generic Claritin, before asking their doctor for an expensive medication.
Related Topics: Plagued by Pollen, Allergy Proof Home Guide
Technorati Tags: hayfever, sudafed, singulair, claritin, decongestant,
During the past couple of years, Singulair has also been marketed for hay fever (allergic rhinitis). However, a study published last month, authored by ENT specialists from Chicago, demonstrated that Singulair, a which costs 3 dollars a day by prescription, was no more effective than sustained-release 240mg Sudafed, an over-the-counter decongestant capsule which costs less than one dollar.
Sudafed was slightly more effective at reducing nasal congestion during the September allergy season in Chicago, and was no more likely to cause side-effects than Singulair.
Homeopathic treatments (equivalent to a placebo) also work rather well for hayfever (allergic rhinitis, sinusitis, and conjunctivitis). A Merck-funded study published in December 2005 [Patel P] showed that 6 weeks of a placebo pill substantially reduced hayfever symptoms in 53% of 1000 adult patients while Singulair did the same for 58% of the other 1000 patients, randomized at 122 medical centers in the United States and Europe. While the difference between 53% and 58% was "statistically significant," the much higher cost of Singulair doesn't seem to me to justify the slightly improved chance of effectiveness. Placebos are also much less likely to cause worrisome dreams than is Singulair.
Patients in the U.S. spend more than 6 billion dollars each year on prescription medicines for hayfever [Yawn, Medscape 2006]. Most of this money is probably spent on non-sedating antihistamines, such as Zyrtec, Clarinex, or Allegra; and for nasal corticosteroid sprays, such as Beconase, Rhinocort, Nasalide, Flonase, Nasonex, or Nasacort. These all cost somebody (patient or insurance) about 75 dollars per month.
However, non-prescription generic Claritin is usually just as effective as the prescription antihistamines and only costs about 3 dollars a month. Rinsing the nose with salt water, such as Sinus Rinse, is even less expensive, often effective at relieving nasal congestion, and has no side-effects. Long-acting nasal decongestant sprays, such as Afrin and generics, can also be used safely for up to ten days, and cost less than 6 dollars for a bottle without a prescription.
In my opinion, people like me with allergic rhinitis should first try the low cost, non-prescription treatments, starting with allergen avoidance, then saline rinses, then generic Claritin, before asking their doctor for an expensive medication.
Related Topics: Plagued by Pollen, Allergy Proof Home Guide
Technorati Tags: hayfever, sudafed, singulair, claritin, decongestant,



12 Comments:
Dr. Enright,
In August of 2002, I was in an SUV roll over. All of the ribs on the right side of my rib cage were broken. Consequently, I suffered a pnemothoraxic injury. I had mild allergies before my accident. My pulmonologist told me that I have a mild form of asthma that developed out of my injury. I had to move to FL to live with my parents, and FL it seems is not the place to live if you have allergies. I sometimes feel a sharp pain in the left medial region of my chest. The pain is worsened when I breath in deeply. I have been examined for cardiac problems, and the report states that nothing remarkable was discovered. Currently, I have a perscription of Allegra D, an Albuterol inhaler, and Flosnoase. All of these meds are PRN. Do you think the chest pain is related to my injury? As I said before, it only hurts ocassionally when I inhale.
Thank You
I would love to use Claritin and if it controled by allergies as well as Allegra I would use it. However, for some reason Claritin and my body do not get along. I agree that using cheaper methods are better and I recently stopped taking Singulair. It was originally prescribed for my allergies, but; since I then needed to add Allegra and my asthma is mild, my doctor and I decided I could stop the Singulair. I haven't noticed any difference. My son also has allergies and he also cannot take Claritin. It makes him drowsy. So although you recommend the inexpensive methods first, they may not always work for some people.
Is this really allergies?
Every year, without fail, since I've lived in Texas (15 years), I get a sinus infection during the first week in May. It always starts out with a sore throat and post nasal drip, then moves into an infection.
I've been on a steroid inhaler this year to try to prevent it, but just like clockwork, this morning, 5/1, I woke up with a sore throat and post nasal drip.
The same thing happens the week surrounding 1/1.
How can this happen? Why can I set my calendar to this versus 2 or three weeks before or 2 or three weeks after 5/1?
I have had severe asthma for 16 years. 14 of those years i have been on prednisone anywhere from 10 mgs up to 5o or 60 mgs. There have only been about 4 weeks of these 16 years that I was able to come off of it. Right now I have been off of it for about 10 days. I came down real slow as to let my body catch up. I have been reading about addison diease and cushing syndrome. Could I develope these? Reason why I am asking. I can hardly get around due to lower back pain and knee pain. Before when i got off, it was my hands, and one time before it was all over my body. I am only 43 but felt like 93. This time has been a lot better, but i just don't have any energy and tire easy. Will I eventually get back to normal or do i need to have my adrenal gland checked? I have had 3 sinsus surgeries to remove polps, 3 knee surgeries and several others. I have osteroarthritis which could be why i hurt. I know the prednisone can cover up alot of other problems.
thanks
This is responding to Jessica - I too had a pheumothorax many years ago and get the same occasional stabbing pain with deep breaths in my chest. These pains are adhesion pains which are common after pneumothorax. They do lessen with time. Hope this helps relieve some anxiety.
Jan, RN
To you who were & are on prednisone for asthma, nasal polyps and surgeries I suggest both Singulair and to get desensitized for Aspirin Allergies. I went to Scripps Institute in La Jolla Ca and have had great results. Their track record on this is remarkable. My sinus Dr. did not know about the correlation between the Aspirin and the reduction of Nasal Polyps. I suffered for 25 years and so has my family members.
Dr. Enright,
I suffer from multiple seasonal and general allergies (trees, grass, ragweed, cockroaches, mold, cats, dogs, latex and shellfish). Shesh. Quite the mix. NOTHING is giving me relief from this allergy mix. At present, I take Nasonex, Allegra and Singulair (I now have astham). Some facts:
1) I developed allergies in my twenties and asthma at 27- prior to my mid twenties I had no problems;
2) I have worked with two allergists and no new treatment is being explored;
3) This year (despite the cold winter season in Canada) I have NOT had relief from my symptoms;
4) I have no pets, don't smoke and keep my home very clean and up to par with allergy free living (ex: covers on bedding etc).
5) It is at the point where my allergies are affecting my mood, workplace productivity and quality of life;
6) I have tried allergy shots but my new allergiest stoped the treatment because of asthma risk;
7) I am willing to try any suggestions!!
What should I do? Where should I turn for new solutions? Should I explore my diet? Any suggestions would be very very helpful
Thanks,
Sheryl
Sheryl,
To ask questions of Dr. Enright, please visit his message board.
Thank you.
I have been on Singulair for two years now and after three winters prior of being asthmatically ill, it was a nice change of pace to find a medication that finally worked. My allergist said that Singulair would also work to treat season allergies, but this allergy season it has not. I've tried Aerus and it has not worked and now I am on Reactine to help combat the allergies I am currently experiencing.
It seems as if my body is starting to reject Singulair... it sure isn't working well!
I recently went into anaphylaxic shock from eating shrimp and have been placed on 150 mg ranitidine. I just got off of a 10 day taper of prednisone or whatever. i also take nexium daily for acid reflux. It has been three weeks since i had the reaction yet my nose is still stopped up and it is somewhat difficult to swallow. Now when I inhale deeply I have pain in my chest. Any ideas what this may be. I had an ekg last week and x-rays of my chest sunday, both were normal. Some have suggested panic attacks but wouldnt my chest hurt for 5-20 minutes and not when I breath deeply.
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regarding anonmyous comment "I have been on Singulair for two years now...It seems as if my body is starting to reject Singulair... it sure isn't working well!"
My son was prescribed Singulair and after taking it for about a month, abruptly stop taking it without my knowledge. Within 3 days of stopping, he had a severe asthma attack totally over the top of what we were used to. It scared the hell out of me. I thought he was going to die, it was so bad. After doing some research (I also have a biology background) I discovered that Singulair is a receptor antigen. I suspect it may cause up regulation of the receptors it blocks, thereby eventually causing the drug to become ineffective, or deadly in the instance an asthmatic is unable to continue to take it, or stops abruptly. Unfortunately, my son is too sensitive to steroids, so we are stuck with Singulair for the time being. At least it is working in the short term, but now your comments have me concerned for the long term. I would love to see some receptor binding assay studies on the drug.
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