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Wednesday, August 01, 2007

Should You Feed "Friendly Bacteria" to Your Infant and Child?
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Here's an unidentified flying fact for your consideration: There are 100 trillion (100,000,000,000,000) bacteria - weighing 4 pounds - happily living in your intestines. That's ten times more bacteria than there are cells in your body, more bacteria than the number of stars in our galaxy, more bacteria than the number of humans who have ever lived (estimated, by the way, at 100 billion) ... You get the picture. There are a lot.

Now that I've completely grossed you out, know this: without these guys, you'd be dead. Some scientists even consider our bacterial inhabitants to be an essential body organ because without them your intestines couldn't properly absorb nutrients, the tissues would be thin and easily torn, your immune system would be compromised, you would become vitamin K deficient, you would be unable to digest certain foods. No wonder, then, that most are called "friendly" (probiotic) bacteria.

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Probiotic bacteria and your infant
When your baby was born her intestines were was completely free of bacteria. Over the first weeks, as she swallowed milk and saliva, various germs entered her gut and took up residence.

Interestingly, these bacteria are different whether a breast- or bottle-feeder, and whether born by C-section or not. Breast-fed and vaginally-born infants are colonized by more of the friendliest guys of all: bifidobacteria, while bottle-fed, C-section delivered infants have far fewer. These bifidobacteria seem especially good in promoting intestinal growth and function, helping the immune system to develop, and playing a role in preventing allergies.

By 12-18 months of age, the bacterial flora (as they are picturesquely called) look pretty much the same no matter what the manner of birth or feeding.

Formulas with friendly bacteria?
Perhaps another reason "breast is best" is because of this effect. That's why you are now reading about infant formulas containing these "friendly" bacteria. Is it a good idea? Should you buy it?

Although the evidence is pretty thin at this point, I'm saying yes to supplementation (much like a vitamin) in the first year of life with bifidobateria and lactobacillus in formula-fed and/or C-section delivered infants. Here's my reasoning:

  • Since your infant's intestines are going to become home to lots of bacteria anyway, why not try to duplicate what generally happens in nature (i.e., in a breast-fed, vaginally-born infant).

  • Bifidobacteria seem to be very safe; there have been no reports of significant medical problems in infants who ingest them. And there seems to be increasing evidence of their positive role in early infant health.

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Other uses of probiotic bacteria in children?
The best evidence for the therapeutic use of probiotic bacteria is during a diarrheal illness (especially rotovirus), where they seem to cut down on the severity and duration of the symptoms. Probiotic bacteria have also have been shown to cut down GI disease in sick, premature infants. Other, less proven, uses have included to prevent infections of the genitourinary tract, to treat irritable bowel syndrome, and to help with preventing and treating eczema in infants.

Again, based on their safety and that it seems to make sense (at least to me), I often recommend using supplements of probiotic bacteria for kids during and after:

  • Infectious diarrhea.

  • Taking antibiotics for any reason.

  • In the care of sick, premature infants (to prevent necrotizing enterocolitis).

  • Symptoms of irritable bowel syndrome.

  • Cases of severe eczema

  • Recurrent urinary tract infections

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Look for supplements containing bifidobacteria and lactobacillus. (There is some debate if yogurt alone can do the trick. Personally I'd count more on the supplements you can buy at your drugstore or health food store).

But beware the exorbitant claims made that these bacteria can prevent cancer and cure other illnesses, which seem pretty dubious to me. Here's what the Harvard Health Letter had to say about this issue (2002):
"Probiotics have been oversold. The claims are that seductive pills, powders, and solutions containing 'friendly' bacteria will boost the immune system, prevent cancer and perform other assorted health miracles...But that doesn't mean it's based on total fiction...The evidence suggests that probiotic therapy could be useful some day as a form of preventive medicine - and not just for diseases affecting the gut."
And since preventive medicine is often best started in infants and children, I'm cautiously coming down on the side of their use, even though the scientific evidence is by no means well established (this is about as "fringey" as I get).

I'm curious: are any of you going down this road? What do your pediatric providers think about this controversial area?

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Posted by: Dr. Parker at 8/01/2007 03:00:00 PM

20 Comments:

Anonymous Anonymous said...

On my pediatrician's advice, I've always given my kids yogurt whenever they have taken antibiotics. Has it helped? I don't know but they have never had diarrhea with the antibiotics.

8/02/2007 08:37:00 AM  
Anonymous Anonymous said...

Sounds like a crock to me. How much is Nestle paying you to promote their stuff?

8/02/2007 05:05:00 PM  
Anonymous Dr. P said...

Your question is legitimate (albeit incredibly snotty). You should wonder if advice-givers have any ulterior motives or agendas.

The answer is I have zero financial interests with any companies of any kind. What I relate is, to the best of my ability, my true opinions based on
my years of practice and experience and thinking about this stuff.

- Dr. P

8/02/2007 10:04:00 PM  
Anonymous julian said...

Nice post, I've been enjoying your blog for awhile. I recommend probiotics for some of the same conditions as above. As a pediatrician who sees a lot of internationally adopted kids, many raised in institutions, I can't help but feel that orphanage residents are the C-section/hospital birth/bottle-fed group to the n-th degree. Not to mention frequent overuse of antibiotics, parasites/giardia in about 10-20%, higher rates of eczema, etc ...

So for this group, I'm cautiously a fan of more routine supplementation after coming home, but I wonder if there's much we can do to permanently alter gut flora in a more "beneficial" direction after 6-12 months old. I've got a post on probiotics on our site as well:
http://www.adoptmed.org/topics/probiotics-and-prebiotics.html

8/03/2007 03:14:00 AM  
Anonymous Anonymous said...

I am 73 and have been using a multi-spectrum probiotic for years to stop diarea and other digestive track disorders. A good multi-spetrum probiotic will have 9 or more strains. Diarea usually stops with two doses of the probiotic. I take it with milk

8/05/2007 11:38:00 AM  
Anonymous Oscar said...

The earlier we develop our immune system, the better. It's in the nature of children to be dirty, because they still don't know what clean is. I believe that this is the best time for children to develop their immune system.

8/06/2007 02:34:00 AM  
Anonymous Yolanda said...

I'm for those probiotic bacterias. What's not to like about it if it helps us in our immune system? We may end up being defenseless without the protection.

8/06/2007 08:52:00 PM  
Anonymous Anonymous said...

Thanks for the info. I hope that others who read your information will hear what I heard; a good reason to give children "good bacteria" AND the importace of breastfeeding. I know how difficult it can be, but it is one of the greatest things we can do for our babies. There is a huge amount of research out there that shows just how helpful breastfeeding is and the reasons just keep on growing.
I hope new moms that are able to, will do it.
Thanks again for your insights.

9/01/2007 01:58:00 PM  
Anonymous Anonymous said...

I believe in probiotic. My son was very sick after taking antibioitcs, and once I give him probiotic, his diaherra stops right away. His ezcema got better too. I think pediatric these days should look into this more. I prefer to have doctors telling me how to strengthen my kids rather than just giving my kid antibiotic everytime he's sick.

10/01/2007 10:54:00 AM  
Anonymous Anonymous said...

My 13 year-old daughter thinks she has IBS. I'm not going to jump-the-gun, but think that her bouts of diarrhea are very much stress-related and possibly hormonal. I'm going to try some probiotics with her to see if it helps her, along with a few dietary changes and exercise. Any thoughts, Dr.P?

11/26/2007 06:58:00 PM  
Anonymous momof2 said...

My son got really sick after taking antibiotics for strep throat-severe stomach pain, cramps, crying, diarrhea. We thought it would pass but didn't-after a stool sample he was diagnosed with c-diff and the doctor recommended a regular regimen of probiotics for him. It has made such a difference. Antiobiotics are sometimes necessary, but always take a probiotic with them-it can't hurt but I promise, from personal experience, it for sure helps!

12/31/2007 08:27:00 PM  
Blogger Kimberlina said...

Both my 1 year old and 3 year old have had recent bouts of sinus infections and had to be on antibiotics for 14 days. They both tend to get terrible yeast diaper rashes when on antibiotics, but this time I supplemented with probiotics. What a difference! No yeast infections, no diarrhea, and happy children!

1/01/2008 09:55:00 PM  
Anonymous allison said...

I had never even thought to use probiotics until our pediatrician mentioned it. He said to give one capsule or a lot of yogurt to our 7month old when starting antibiotics to prevent diarrhea. She had a terrible bout or diarrhea followed by really bad diaper rash the month before. So this time I tried it and oh did it work. We are now on another round of antibiotics (another ear infection) and I did the same treatment, no diarrhea therefore no diaper rash. I am a nurse and had never considered giving this to my children and now will not give antibiotics without it. I am not looking forward to a diarrhea virus in the future but will certainly be more proactive and give probiotics.

1/06/2008 09:34:00 PM  
Anonymous Anonymous said...

I'm 31 just left hospital 3 hour's ago. Diagnosed with c-diff and colitis.I was on two antibiotic's for 5 day's. Flagyl for bacterial ifection. Ammoxicillion for a cold.Now those caused c-diff. my med's they sent me home with cost me 1,333.77 after insurance. I'm weak , sick,and very upset

1/18/2008 11:12:00 PM  
Blogger tiffany said...

Probiotics have literally helped in my 3 year olds bouts of c-diff
greatly. She was diagnosed as being a carrier of this and we were
constantly battling with 10 cases of diarrhea a day. Culturelle has nearly stopped this problem.

1/22/2008 11:38:00 AM  
Anonymous Trish said...

a bit around the subject...i cant find answers. my dr never gave my baby his vitamin k shot at birth or supp ant all. he has had some issue with blood clotting at 1 week old during his circ, and regenerating enough red blood cells to raise is hemaglobin( so he is a bit animic... so i have to give him extra iron) also he has a heart murmur and fast breathiing.

I am concerned it is connected and what other problems it can cause if any.

and does vitamin k difeciency correct itself?

Kayden is 9 weeks and 100% breastfed.

I would appriciate anyone who knew about this..

Trish
Trishdarling@sbcglobal.net

1/24/2008 08:19:00 PM  
Anonymous Anonymous said...

Has anyone looked into giving probiotics instead of a vitamin K injection at birth to prevent vitamin K deficiency bleeding? How long would it take probiotics to work so that the infant would produce enough vitamin K?

4/05/2008 02:15:00 AM  
Anonymous Anonymous said...

After being diagnosed with C-diff and starting the recommended treatment of Flagyl for 14 days; how long are you infectious to others?

I have been fighting C-Diff for two years after a hospital procedure. It's VERY upsetting.

I'm also on coumadin to thin my blood since I have a new aortic valve so I question if probiotics would be compromising my coumadin issues. It seems EVERYTHING affects it.

I could use some advise. : )
Demi

4/11/2008 08:15:00 AM  
Anonymous Anonymous said...

My son is 9 months old and was diagnosed with c-diff.He has never been on a antibiotic (except for now)and is up to date on all his shots. His diet is baby food except cheerios. I dont understand how he could have picked this up. During the day he is taken care of by his grandma no other kids present. At home he has 3 sisters and nobody between the two houses have been sick. Any ideas or similiar cases? thanks.

5/20/2008 08:15:00 PM  
Anonymous Anonymous said...

I have been on flagyl for ten days now. It made me very sick with side effects. Not too bad in the beginning, then all of a sudden...
I was told that I did get mild c. diff from ZPac for treating my ear cold. I have one pill left and can't wait for this all to hopefully be over. I never thought that taking medicine to make you well could make you so very ill.

7/18/2008 08:43:00 PM  

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