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Sleep disorders include a range of problems -- from insomnia to narcolepsy -- and affect millions of Americans. Dr. Michael Breus shares information and advice on sleep disorder and insomnia treatments and causes.

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WebMD Health News

Monday, November 19, 2007

Statins Linked to Nightmares and Insomnia
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It was only a matter of time. A few years ago, statins were hailed as the miracle drugs of the decade - helping people to lower their cholesterol effectively and reduce their risk for heart attacks and cardiovascular disease. Statins are bestselling drugs globally, accounting for more than $14 billion in sales in the United States alone. Some doctors have suggested that more prescribed statins can help save millions more each year.

But the noise on the other side of the table is growing louder and gaining momentum as a handful of experts ponder the financial, physical, and ethical implications of relying on statins to, quite literally, fund a fatty lifestyle. Is it okay to have your cake and eat it too so long as you pop a super pill?

But now there's even more fuel to the debate. Last week I read an article online pointing to new research from the American Heart Association detailing side effects previously unidentified. Turns out some statins - particularly the kind that get absorbed into the brain - can mess with sleep and provoke nightmares and insomnia. These statins include Zocor, Lipitor, Mevacor, and Vytorin. People on Pravachol and Crestor, which do not get into the brain so easily, seem to avoid the troubled sleep.

Two items to note about this finding. One is, how many people on these medications experience restless sleep but never think to link it to their meds? (Not to mention the fact their doctors are likely not asking them about sleep. Cardiologists are more concerned about a statin's effect on the liver than on sleep.)

And second, how many statin addicts continue to eat poorly and keep extra weight on? Scores of studies have linked poor sleep habits to becoming overweight and more prone to health problems including obesity, diabetes, and heart disease. But now that one of our most trusted treatments for high cholesterol is pegged with a new warning sign, we are left wondering exactly which comes first in the proverbial chicken-egg enigma: Can statins trigger poor sleep, which then sets the stage for gaining weight, becoming obese, perhaps dealing with sleep apnea on top of all that weight, and a higher risk for heart troubles?

In other words, can statins ultimately have the opposite effect from what they are intended to do by virtue of this cascade?

Granted, statins do have a powerful effect on many and they may be the best solution for those stuck with genetics that call for high cholesterol. But one has to wonder the ultimate cost of these drugs on people. Every year we seem to add one more side effect to the list. If you can control cholesterol relatively well through your lifestyle (i.e., diet and exercise), eat your Cheerios and oatmeal and practice good sleep habits, you stand to gain more than a happy heart. I bet you'd welcome a flurry of positive outcomes, the least of which is no longer needing any medication.

Which leads me to believe that some day we'll see cardiologists prescribing sleep as a partnering remedy for high cholesterol alongside diet and exercise. How dreamy is that?

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Posted by: Dr. Breus at 8:26 PM

5 Comments:

Anonymous Anonymous said...

I take vytorin and have nightmares. I was blaming it on vicodin which I take for degenerative dfisc problems. I also have muscle problems, which I think vytorin is causing.

9:11 PM  
Anonymous Anonymous said...

I had the nightmares too and flash-backs during the day of not so pleasant things that happened in my life.

I took Vytorin for less than 6 weeks and could tell that muscle weakness was starting. Tests confirmed this. I am still dealing with loss of muscle and loose skin.

11:44 PM  
Blogger Marty said...

I am taking 20mg Lipitor and simply can not sleep! Is there anything anyone can suggest to help with this? I already take it in the morning, and please don't suggest spraying some scent on my pillow as strong aromas are an asthma trigger for me. It's 2:51 AM right now... and I was ALWAYS asleep by 10 with no problems. Now I rarely get to sleep until about 4AM, and then I have to get up at 6. Aaaaaargh! Marty in NC

2:48 AM  
Anonymous Anonymous said...

I started taking 20mg of Zocor 3 mos. ago. My cholestorol is down from 265 to 210. The bad news is I'm getting some bad nightmares. I'm almost afraid to go to sleep.

The other problem is my weight has gone up even though I usually lose this time of year from bike riding. I do 100 miles a week. I should be 10 to 15 lbs. lighter and instead I gained 5 lbs. and I'm not eating any more than usual.

So far, I don't think I have any muscle problems. The doctor told me to lift weights

12:42 AM  
Anonymous Anonymous said...

i was taking 10mg of lipitor for 2-21/2 years then after blood work and my cholestrol got high again, i was put on 20mg. I had to go off the lipitor to take cipro for a UTI, which really didnt agree with me. I dont feel any different being off the lipitor so far. It has only been a week. I stopped taking the cipro because I was so sick on it that I could hardly walk. I started taking more acidophilis and and changed my multivitamin to One a day essential, bought some blueberries and craisins and I am finally feeling better. My pharmacist told me not to take the cipro because i had severe side effects from levoquin which is also a quinolone but my doctor insisted. so glad that I stopped because i finally feel better after 3 weeks or more. I am seeing a urologist on july 16 to see what he thinks.

I think that is may be caused from the lipitor. I only had one other UTI in my life and that was shortly after I started taking the 10mg. This one is 10x worse. Hope that this helps someone.

7:37 PM  

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