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Can PRP Injections Really Give You a Bigger Penis?

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Sheldon Marks, MD - Blogs
By Sheldon Marks, MDBoard-certified urologistJune 27, 2016
From the WebMD Archives

If you’re unhappy with what you’ve got down below, you’re not alone – a lot of guys want to trump nature and increase the size of their penis. They’re constantly on the lookout for a new product or treatment that will give them a bigger package.

A new one on the market injects platelet rich plasma (PRP) into your penis to make it bigger. Widely marketed as The Priapus Shot™, invented by Dr. Charles Runels, hype about the treatment is growing. But is there proof that this new treatment will really it bigger? Will this really strengthen the penis or increase stamina, sensation and pleasure? And what are the risks of trying it (as there are always risks)?

Let’s talk about what the injection is, exactly. First, your own blood is drawn, then the platelets are concentrated. This platelet-rich plasma is then re-injected into your penis. The treatment is supposed to stimulate regrowth of new tissues and after one or more injections, lead to a bigger penis. Some marketers claim that the injection will increase penis size as much as 10 to 20% in length and girth.

In theory, the idea makes sense: use the body’s own healing mechanisms, goosed to new levels, to rejuvenate your penis to be bigger and work better.

But there are a couple of problems with this theory.

First, while it may be possible to temporarily increase girth by injecting temporary fillers and fluid into the tissues (just think of those women with swollen, puffy lips from collagen), you can’t permanently change what you were genetically given. The two internal chambers (corpora cavernosa) that allow a penis to expand in length and girth with erections are fixed in size. No amount of stretching, injecting, vitamins, surgery or hormones can make them any bigger. As an old professor of mine once explained, “they are what they are.”

Another problem with the theory: platelet-rich plasma injections prompt healing, not growth. Platelets accelerate healing of an injury by increasing inflammation (swelling) and growth of microscopic blood vessels. Platelet-rich plasma is often injected at the site of an injury to accelerate the rebuilding of the damaged tissue and restore the area to its original condition. So, PRP injections can be a helpful means to boost healing and tissue regeneration after orthopedic injuries, plastic surgery or for bad arthritis, but they’re not going to make those areas bigger or better than they were before the injury.

Plus, when it comes to injecting PRP into penises, we just don’t have enough research.

There are only 2 studies on platelet-rich plasma injections in penises – and those are in rat penises, after their genital nerves had been crushed. The studies did show that the treated rats had faster regeneration of the nerves, and consequently, better restoration of erections, than non-treated rat penises – but neither study showed that the treated rats ended up with bigger penises. Looking through hundreds of studies, I can find none aimed at testing using PRP in humans to make penises bigger. I did locate a Russian research paper indicating that it might be worthwhile to research the use of PRP in men for erectile dysfunction – and I agree that this is worth looking into – but the paper offered no other information, and no mention of using PRP to increase penis size. Of the research listed on The Priapus Shot™ website, only one of the studies was specific to penises, and it focused on correcting curved penises. So, as of right now, there are no studies to prove that PRP makes healthy penises bigger, neither in rats nor men.

If, despite all of this, you are still considering this treatment, you should consider the risks. Though I am sure that some men will complain of pain, I am more worried that repeated injections might lead to scarred, disfigured penises. Plus there are some concerns about rare risks leading to life threatening blood-clotting problems.

For a lot of men who have been searching for a way to increase their size, this treatment may sound like the Holy Grail. But there is no evidence to show it is scientifically proven to work as claimed and it has not been thoroughly tested for safety. Additionally, at a cost of several thousand dollars per shot, it’s an expensive gamble. Unless new research comes to light, I won’t be recommending this treatment to my patients.

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About the Author
Sheldon Marks, MD

Sheldon Marks, MD, is director of the International Center for Vasectomy Reversal in Tucson, one of the leading specialty centers in the world. Dr. Marks is a best-selling author and frequently teaches other urologists about advances and techniques with vasectomy reversals. He has been writing for WebMD since 2005.

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